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Controlling Immune Rejection Is a Fail-Safe System against Potential Tumorigenicity after Human iPSC-Derived Neural Stem Cell Transplantation

Our previous work reported functional recovery after transplantation of mouse and human induced pluripotent stem cell-derived neural stem/progenitor cells (hiPSC-NS/PCs) into rodent models of spinal cord injury (SCI). Although hiPSC-NS/PCs proved useful for the treatment of SCI, the tumorigenicity o...

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Detalles Bibliográficos
Autores principales: Itakura, Go, Kobayashi, Yoshiomi, Nishimura, Soraya, Iwai, Hiroki, Takano, Morito, Iwanami, Akio, Toyama, Yoshiaki, Okano, Hideyuki, Nakamura, Masaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338009/
https://www.ncbi.nlm.nih.gov/pubmed/25706286
http://dx.doi.org/10.1371/journal.pone.0116413