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The Frequency-Response Electroretinogram Distinguishes Cone and Abnormal Rod Function in rd12 Mice

Early studies on Rpe65 knockout mice reported that remaining visual function was attributable to cone function. However, this finding has been challenged more and more as time has passed. Electroretinograms (ERGs) showed that rd12 mice, a spontaneous animal model of RPE65 Leber’s congenital amaurosi...

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Detalles Bibliográficos
Autores principales: Dai, Xufeng, Zhang, Hua, He, Ying, Qi, Yan, Chang, Bo, Pang, Ji-jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338143/
https://www.ncbi.nlm.nih.gov/pubmed/25706871
http://dx.doi.org/10.1371/journal.pone.0117570