Rhodopsin kinase and recoverin modulate phosphodiesterase during mouse photoreceptor light adaptation

Light stimulates rhodopsin in a retinal rod to activate the G protein transducin, which binds to phosphodiesterase (PDE), relieving PDE inhibition and decreasing guanosine 3′,5′-cyclic monophosphate (cGMP) concentration. The decrease in cGMP closes outer segment channels, producing the rod electrica...

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Detalles Bibliográficos
Autores principales: Chen, Ching-Kang, Woodruff, Michael L., Fain, Gordon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338159/
https://www.ncbi.nlm.nih.gov/pubmed/25667411
http://dx.doi.org/10.1085/jgp.201411273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338159/
https://www.ncbi.nlm.nih.gov/pubmed/25667411
http://dx.doi.org/10.1085/jgp.201411273

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