The New 4-O-Methylhonokiol Analog GS12021 Inhibits Inflammation and Macrophage Chemotaxis: Role of AMP-Activated Protein Kinase α Activation

Preventing pathologic tissue inflammation is key to treating obesity-induced insulin resistance and type 2 diabetes. Previously, we synthesized a series of methylhonokiol analogs and reported that compounds with a carbamate structure had inhibitory function against cyclooxygenase-2 in a cell-free en...

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Detalles Bibliográficos
Autores principales: Kim, Sora, Ka, Sun-O, Lee, Youngyi, Park, Byung-Hyun, Fei, Xiang, Jung, Jae-Kyung, Seo, Seung-Yong, Bae, Eun Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338227/
https://www.ncbi.nlm.nih.gov/pubmed/25706552
http://dx.doi.org/10.1371/journal.pone.0117120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338227/
https://www.ncbi.nlm.nih.gov/pubmed/25706552
http://dx.doi.org/10.1371/journal.pone.0117120

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