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Hierarchical Clustering of Breast Cancer Methylomes Revealed Differentially Methylated and Expressed Breast Cancer Genes

Oncogenic transformation of normal cells often involves epigenetic alterations, including histone modification and DNA methylation. We conducted whole-genome bisulfite sequencing to determine the DNA methylomes of normal breast, fibroadenoma, invasive ductal carcinomas and MCF7. The emergence, disap...

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Detalles Bibliográficos
Autores principales: Lin, I-Hsuan, Chen, Dow-Tien, Chang, Yi-Feng, Lee, Yu-Ling, Su, Chia-Hsin, Cheng, Ching, Tsai, Yi-Chien, Ng, Swee-Chuan, Chen, Hsiao-Tan, Lee, Mei-Chen, Chen, Hong-Wei, Suen, Shih-Hui, Chen, Yu-Cheng, Liu, Tze-Tze, Chang, Chuan-Hsiung, Hsu, Ming-Ta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338251/
https://www.ncbi.nlm.nih.gov/pubmed/25706888
http://dx.doi.org/10.1371/journal.pone.0118453