Activin-A and Bmp4 Levels Modulate Cell Type Specification during CHIR-Induced Cardiomyogenesis

The use of human pluripotent cell progeny for cardiac disease modeling, drug testing and therapeutics requires the ability to efficiently induce pluripotent cells into the cardiomyogenic lineage. Although direct activation of the Activin-A and/or Bmp pathways with growth factors yields context-depen...

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Detalles Bibliográficos
Autores principales: Kim, Min-Su, Horst, Audrey, Blinka, Steven, Stamm, Karl, Mahnke, Donna, Schuman, James, Gundry, Rebekah, Tomita-Mitchell, Aoy, Lough, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338295/
https://www.ncbi.nlm.nih.gov/pubmed/25706534
http://dx.doi.org/10.1371/journal.pone.0118670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338295/
https://www.ncbi.nlm.nih.gov/pubmed/25706534
http://dx.doi.org/10.1371/journal.pone.0118670

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