Cargando…

Decreased expression of hepatic glucokinase in type 2 diabetes

BACKGROUND/OBJECTIVES: Increased endogenous glucose production is a hallmark of type 2 diabetes. Evidence from animal models has suggested that a likely cause of this is increased mRNA expression of glucose 6-phosphatase and phosphoenolpyruvate carboxykinase (encoded by G6PC, PCK1 and PCK2). But ano...

Descripción completa

Detalles Bibliográficos
Autores principales: Haeusler, Rebecca A., Camastra, Stefania, Astiarraga, Brenno, Nannipieri, Monica, Anselmino, Marco, Ferrannini, Ele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338311/
https://www.ncbi.nlm.nih.gov/pubmed/25737948
http://dx.doi.org/10.1016/j.molmet.2014.12.007