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Decreased expression of hepatic glucokinase in type 2 diabetes

BACKGROUND/OBJECTIVES: Increased endogenous glucose production is a hallmark of type 2 diabetes. Evidence from animal models has suggested that a likely cause of this is increased mRNA expression of glucose 6-phosphatase and phosphoenolpyruvate carboxykinase (encoded by G6PC, PCK1 and PCK2). But ano...

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Detalles Bibliográficos
Autores principales:	Haeusler, Rebecca A., Camastra, Stefania, Astiarraga, Brenno, Nannipieri, Monica, Anselmino, Marco, Ferrannini, Ele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338311/ https://www.ncbi.nlm.nih.gov/pubmed/25737948 http://dx.doi.org/10.1016/j.molmet.2014.12.007

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