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NPY signalling in early osteoblasts controls glucose homeostasis

OBJECTIVE: The skeleton has recently emerged as an additional player in the control of whole-body glucose metabolism; however, the mechanism behind this is not clear. METHODS: Here we employ mice lacking neuropeptide Y, Y1 receptors solely in cells of the early osteoblastic lineage (Y1f3.6Cre), to e...

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Detalles Bibliográficos
Autores principales: Lee, Nicola J., Nguyen, Amy D., Enriquez, Ronaldo F., Luzuriaga, Jude, Bensellam, Mohammed, Laybutt, Ross, Baldock, Paul A., Herzog, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338316/
https://www.ncbi.nlm.nih.gov/pubmed/25737952
http://dx.doi.org/10.1016/j.molmet.2014.12.010