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Prp40 pre-mRNA processing factor 40 homolog B (PRPF40B) associates with SF1 and U2AF(65) and modulates alternative pre-mRNA splicing in vivo
The first stable complex formed during the assembly of spliceosomes onto pre-mRNA substrates in mammals includes U1 snRNP, which recognizes the 5′ splice site, and the splicing factors SF1 and U2AF, which bind the branch point sequence, polypyrimidine tract, and 3′ splice site. The 5′ and 3′ splice...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338339/ https://www.ncbi.nlm.nih.gov/pubmed/25605964 http://dx.doi.org/10.1261/rna.047258.114 |