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Efficient backsplicing produces translatable circular mRNAs

While the human transcriptome contains a large number of circular RNAs (circRNAs), the functions of most circRNAs remain unclear. Sequence annotation suggests that most circRNAs are generated from splicing in reversed orders across exons. However, the mechanisms of this backsplicing are largely unkn...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Wang, Zefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338345/
https://www.ncbi.nlm.nih.gov/pubmed/25449546
http://dx.doi.org/10.1261/rna.048272.114