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WBSCR22/Merm1 is required for late nuclear pre-ribosomal RNA processing and mediates N(7)-methylation of G1639 in human 18S rRNA
Ribosomal (r)RNAs are extensively modified during ribosome synthesis and their modification is required for the fidelity and efficiency of translation. Besides numerous small nucleolar RNA-guided 2′-O methylations and pseudouridinylations, a number of individual RNA methyltransferases are involved i...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338346/ https://www.ncbi.nlm.nih.gov/pubmed/25525153 http://dx.doi.org/10.1261/rna.047910.114 |