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WBSCR22/Merm1 is required for late nuclear pre-ribosomal RNA processing and mediates N(7)-methylation of G1639 in human 18S rRNA

Ribosomal (r)RNAs are extensively modified during ribosome synthesis and their modification is required for the fidelity and efficiency of translation. Besides numerous small nucleolar RNA-guided 2′-O methylations and pseudouridinylations, a number of individual RNA methyltransferases are involved i...

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Detalles Bibliográficos
Autores principales: Haag, Sara, Kretschmer, Jens, Bohnsack, Markus T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338346/
https://www.ncbi.nlm.nih.gov/pubmed/25525153
http://dx.doi.org/10.1261/rna.047910.114