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Functional importance of Ψ(38) and Ψ(39) in distinct tRNAs, amplified for tRNA(Gln(UUG)) by unexpected temperature sensitivity of the s(2)U modification in yeast

The numerous modifications of tRNA play central roles in controlling tRNA structure and translation. Modifications in and around the anticodon loop often have critical roles in decoding mRNA and in maintaining its reading frame. Residues U(38) and U(39) in the anticodon stem–loop are frequently modi...

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Detalles Bibliográficos
Autores principales: Han, Lu, Kon, Yoshiko, Phizicky, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338347/
https://www.ncbi.nlm.nih.gov/pubmed/25505024
http://dx.doi.org/10.1261/rna.048173.114