An evolutionary approach uncovers a diverse response of tRNA 2-thiolation to elevated temperatures in yeast

Chemical modifications of transfer RNA (tRNA) molecules are evolutionarily well conserved and critical for translation and tRNA structure. Little is known how these nucleoside modifications respond to physiological stress. Using mass spectrometry and complementary methods, we defined tRNA modificati...

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Detalles Bibliográficos
Autores principales: Alings, Fiona, Sarin, L. Peter, Fufezan, Christian, Drexler, Hannes C.A., Leidel, Sebastian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338348/
https://www.ncbi.nlm.nih.gov/pubmed/25505025
http://dx.doi.org/10.1261/rna.048199.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338348/
https://www.ncbi.nlm.nih.gov/pubmed/25505025
http://dx.doi.org/10.1261/rna.048199.114

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