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An evolutionary approach uncovers a diverse response of tRNA 2-thiolation to elevated temperatures in yeast
Chemical modifications of transfer RNA (tRNA) molecules are evolutionarily well conserved and critical for translation and tRNA structure. Little is known how these nucleoside modifications respond to physiological stress. Using mass spectrometry and complementary methods, we defined tRNA modificati...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338348/ https://www.ncbi.nlm.nih.gov/pubmed/25505025 http://dx.doi.org/10.1261/rna.048199.114 |