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Refined secondary-structure models of the core of yeast and human telomerase RNAs directed by SHAPE
Telomerase catalyzes the addition of nucleotides to the ends of chromosomes to complete genomic DNA replication in eukaryotes and is implicated in multiple diseases, including most cancers. The core enzyme is composed of a reverse transcriptase and an RNA subunit, which provides the template for DNA...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338352/ https://www.ncbi.nlm.nih.gov/pubmed/25512567 http://dx.doi.org/10.1261/rna.048959.114 |