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Hyperhomocysteinemia and MTHFR Polymorphisms as Antenatal Risk Factors of White Matter Abnormalities in Two Cohorts of Late Preterm and Full Term Newborns

Higher total homocysteine (tHcy) levels, and C677T and A1298C methylenetetrahydrofolate (MTHFR) polymorphisms, have been reported in preterm or full term newborns with neonatal encephalopathy following perinatal hypoxic-ischemic insult. This study investigated the causal role of tHcy and MTHFR polym...

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Detalles Bibliográficos
Autores principales: Marseglia, Lucia M., Nicotera, Antonio, Salpietro, Vincenzo, Giaimo, Elisa, Cardile, Giovanna, Bonsignore, Maria, Alibrandi, Angela, Caccamo, Daniela, Manti, Sara, D'Angelo, Gabriella, Mamì, Carmelo, Di Rosa, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338403/
https://www.ncbi.nlm.nih.gov/pubmed/25829992
http://dx.doi.org/10.1155/2015/543134