The TLR4 Agonist Fibronectin Extra Domain A is Cryptic, Exposed by Elastase-2; use in a fibrin matrix cancer vaccine

Fibronectin (FN) is an extracellular matrix (ECM) protein including numerous fibronectin type III (FNIII) repeats with different functions. The alternatively spliced FN variant containing the extra domain A (FNIII EDA), located between FNIII 11 and FNIII 12, is expressed in sites of injury, chronic...

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Detalles Bibliográficos
Autores principales: Julier, Ziad, Martino, Mikaël M., de Titta, Alexandre, Jeanbart, Laura, Hubbell, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338432/
https://www.ncbi.nlm.nih.gov/pubmed/25708982
http://dx.doi.org/10.1038/srep08569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338432/
https://www.ncbi.nlm.nih.gov/pubmed/25708982
http://dx.doi.org/10.1038/srep08569

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