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Enrichment of CD56(dim)KIR+CD57+ highly cytotoxic NK cells in tumor infiltrated lymph nodes of melanoma patients

An important checkpoint in the progression of melanoma is the metastasis to lymph nodes. Here, to investigate the role of lymph node NK cells in disease progression, we analyze frequency, phenotype and functions of NK cells from tumor-infiltrated (TILN) and tumor-free ipsilateral lymph nodes (TFLN)...

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Detalles Bibliográficos
Autores principales: Ali, Talib Hassan, Pisanti, Simona, Ciaglia, Elena, Mortarini, Roberta, Anichini, Andrea, Garofalo, Cinzia, Tallerico, Rossana, Santinami, Mario, Gulletta, Elio, Ietto, Caterina, Galgani, Mario, Matarese, Giuseppe, Bifulco, Maurizio, Ferrone, Soldano, Colucci, Francesco, Moretta, Alessandro, Kärre, Klas, Carbone, Ennio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338526/
https://www.ncbi.nlm.nih.gov/pubmed/25472612
http://dx.doi.org/10.1038/ncomms6639