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A PP1/PP2A phosphatase relay controls mitotic progression

The widespread reorganisation of cellular architecture in mitosis is achieved through extensive protein phosphorylation, driven by the coordinated activation of a mitotic kinase network and repression of counteracting phosphatases. Phosphatase activity must subsequently be restored to promote mitoti...

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Detalles Bibliográficos
Autores principales: Grallert, Agnes, Boke, Elvan, Hagting, Anja, Hodgson, Ben, Connolly, Yvonne, Griffiths, John. R., Smith, Duncan L., Pines, Jonathon, Hagan, Iain M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338534/
https://www.ncbi.nlm.nih.gov/pubmed/25487150
http://dx.doi.org/10.1038/nature14019