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Mesenchymal stromal cells induce epithelial-to-mesenchymal transition in human colorectal cancer cells through the expression of surface-bound TGF-β

Mesenchymal stem/stromal cells (MSC) are multipotent precursors endowed with the ability to home to primary and metastatic tumor sites, where they can integrate into the tumor-associated stroma. However, molecular mechanisms and outcome of their interaction with cancer cells have not been fully clar...

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Detalles Bibliográficos
Autores principales: Mele, Valentina, Muraro, Manuele G, Calabrese, Diego, Pfaff, Dennis, Amatruda, Nunzia, Amicarella, Francesca, Kvinlaug, Brynn, Bocelli-Tyndall, Chiara, Martin, Ivan, Resink, Therese J, Heberer, Michael, Oertli, Daniel, Terracciano, Luigi, Spagnoli, Giulio C, Iezzi, Giandomenica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338537/
https://www.ncbi.nlm.nih.gov/pubmed/24214914
http://dx.doi.org/10.1002/ijc.28598