Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes

Cancer is a genetic disease, but two patients rarely have identical genotypes. Similarly, patients differ in their clinicopathological parameters, but how genotypic and phenotypic heterogeneity are interconnected is not well understood. Here we build statistical models to disentangle the effect of 1...

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Detalles Bibliográficos
Autores principales: Gerstung, Moritz, Pellagatti, Andrea, Malcovati, Luca, Giagounidis, Aristoteles, Porta, Matteo G Della, Jädersten, Martin, Dolatshad, Hamid, Verma, Amit, Cross, Nicholas C. P., Vyas, Paresh, Killick, Sally, Hellström-Lindberg, Eva, Cazzola, Mario, Papaemmanuil, Elli, Campbell, Peter J., Boultwood, Jacqueline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338540/
https://www.ncbi.nlm.nih.gov/pubmed/25574665
http://dx.doi.org/10.1038/ncomms6901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338540/
https://www.ncbi.nlm.nih.gov/pubmed/25574665
http://dx.doi.org/10.1038/ncomms6901

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