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Innate sensing of microbial products promotes wound-induced skin cancer

The association between tissue damage, chronic inflammation and cancer is well known. However, the underlying mechanisms are unclear. Here we characterize a mouse model in which constitutive epidermal extracellular-signal-regulated kinase-MAP-kinase signalling results in epidermal inflammation, and...

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Detalles Bibliográficos
Autores principales: Hoste, Esther, Arwert, Esther N., Lal, Rohit, South, Andrew P., Salas-Alanis, Julio C., Murrell, Dedee F., Donati, Giacomo, Watt, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338544/
https://www.ncbi.nlm.nih.gov/pubmed/25575023
http://dx.doi.org/10.1038/ncomms6932