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Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution

The ryanodine receptors (RyRs) are high-conductance intracellular Ca(2+) channels that play a pivotal role in the excitation-contraction coupling of skeletal and cardiac muscles. RyRs are the largest known ion channels, with a homotetrameric organization and approximately 5000 residues in each proto...

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Detalles Bibliográficos
Autores principales: Yan, Zhen, Bai, Xiaochen, Yan, Chuangye, Wu, Jianping, Li, Zhangqiang, Xie, Tian, Peng, Wei, Yin, Changcheng, Li, Xueming, Scheres, Sjors H.W., Shi, Yigong, Yan, Nieng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338550/
https://www.ncbi.nlm.nih.gov/pubmed/25517095
http://dx.doi.org/10.1038/nature14063