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BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells

Triple-negative breast cancer (TNBC) has poor prognostic outcome compared with other types of breast cancer. The molecular and cellular mechanisms underlying TNBC pathology are not fully understood. Here, we report that the transcription factor BCL11A is overexpressed in TNBC including basal-like br...

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Detalles Bibliográficos
Autores principales: Khaled, Walid T., Choon Lee, Song, Stingl, John, Chen, Xiongfeng, Raza Ali, H., Rueda, Oscar M., Hadi, Fazal, Wang, Juexuan, Yu, Yong, Chin, Suet-Feung, Stratton, Mike, Futreal, Andy, Jenkins, Nancy A., Aparicio, Sam, Copeland, Neal G., Watson, Christine J., Caldas, Carlos, Liu, Pentao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338552/
https://www.ncbi.nlm.nih.gov/pubmed/25574598
http://dx.doi.org/10.1038/ncomms6987