Cargando…
BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells
Triple-negative breast cancer (TNBC) has poor prognostic outcome compared with other types of breast cancer. The molecular and cellular mechanisms underlying TNBC pathology are not fully understood. Here, we report that the transcription factor BCL11A is overexpressed in TNBC including basal-like br...
Autores principales: | Khaled, Walid T., Choon Lee, Song, Stingl, John, Chen, Xiongfeng, Raza Ali, H., Rueda, Oscar M., Hadi, Fazal, Wang, Juexuan, Yu, Yong, Chin, Suet-Feung, Stratton, Mike, Futreal, Andy, Jenkins, Nancy A., Aparicio, Sam, Copeland, Neal G., Watson, Christine J., Caldas, Carlos, Liu, Pentao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338552/ https://www.ncbi.nlm.nih.gov/pubmed/25574598 http://dx.doi.org/10.1038/ncomms6987 |
Ejemplares similares
-
Bcl11a is essential for lymphoid development and negatively regulates p53
por: Yu, Yong, et al.
Publicado: (2012) -
The transcription factor Bcl11b is specifically expressed in group 2 innate lymphoid cells and is essential for their development
por: Yu, Yong, et al.
Publicado: (2015) -
Genome-driven integrated classification of breast cancer validated in over 7,500 samples
por: Ali, H Raza, et al.
Publicado: (2014) -
BCL11B is required for positive selection and survival of double-positive thymocytes
por: Albu, Diana I., et al.
Publicado: (2007) -
A dual function of Bcl11b/Ctip2 in hippocampal neurogenesis
por: Simon, Ruth, et al.
Publicado: (2012)