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Charge-driven dynamics of nascent chain movement through the SecYEG translocon
On average, every fifth residue in secretory proteins carries either a positive or a negative charge. In a bacterium such as Escherichia coli, charged residues are exposed to an electric field as they transit through the inner membrane, which should generate a fluctuating electric force on a translo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338579/ https://www.ncbi.nlm.nih.gov/pubmed/25558985 http://dx.doi.org/10.1038/nsmb.2940 |