Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env

HIV’s envelope glycoprotein (Env) is the sole target for neutralizing antibodies. The structures of many broadly neutralizing antibodies (bNAbs) in complex with truncated Env subunits or components have been reported. However, their interaction with the intact Env trimer, and the structural determin...

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Detalles Bibliográficos
Autores principales: Guttman, Miklos, Cupo, Albert, Julien, Jean-Philippe, Sanders, Rogier W., Wilson, Ian A., Moore, John P., Lee, Kelly K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338595/
https://www.ncbi.nlm.nih.gov/pubmed/25652336
http://dx.doi.org/10.1038/ncomms7144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338595/
https://www.ncbi.nlm.nih.gov/pubmed/25652336
http://dx.doi.org/10.1038/ncomms7144

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