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Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env
HIV’s envelope glycoprotein (Env) is the sole target for neutralizing antibodies. The structures of many broadly neutralizing antibodies (bNAbs) in complex with truncated Env subunits or components have been reported. However, their interaction with the intact Env trimer, and the structural determin...
Autores principales: | Guttman, Miklos, Cupo, Albert, Julien, Jean-Philippe, Sanders, Rogier W., Wilson, Ian A., Moore, John P., Lee, Kelly K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338595/ https://www.ncbi.nlm.nih.gov/pubmed/25652336 http://dx.doi.org/10.1038/ncomms7144 |
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