Evaluation of sulfobutylether-β-cyclodextrin (SBECD) accumulation and voriconazole pharmacokinetics in critically ill patients undergoing continuous renal replacement therapy

INTRODUCTION: Intravenous (IV) voriconazole is not recommended in patients with creatinine clearance <50 ml/min to avoid potentially toxic accumulation of sulfobutylether-β-cyclodextrin (SBECD). The purpose of this study was to evaluate the pharmacokinetics of SBECD, voriconazole, and voriconazol...

Descripción completa

Detalles Bibliográficos
Autores principales: Kiser, Tyree H, Fish, Douglas N, Aquilante, Christina L, Rower, Joseph E, Wempe, Michael F, MacLaren, Robert, Teitelbaum, Isaac
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338618/
https://www.ncbi.nlm.nih.gov/pubmed/25645660
http://dx.doi.org/10.1186/s13054-015-0753-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338618/
https://www.ncbi.nlm.nih.gov/pubmed/25645660
http://dx.doi.org/10.1186/s13054-015-0753-8

Ejemplares similares