Comparison of MAPK specificity across the ETS transcription factor family identifies a high-affinity ERK interaction required for ERG function in prostate cells

BACKGROUND: The RAS/MAPK signaling pathway can regulate gene expression by phosphorylating and altering the function of some, but not all, ETS transcription factors. ETS family transcription factors bind similar DNA sequences and can compete for genomic binding sites. However, MAPK regulation varies...

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Detalles Bibliográficos
Autores principales: Selvaraj, Nagarathinam, Kedage, Vivekananda, Hollenhorst, Peter C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338625/
https://www.ncbi.nlm.nih.gov/pubmed/25885538
http://dx.doi.org/10.1186/s12964-015-0089-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338625/
https://www.ncbi.nlm.nih.gov/pubmed/25885538
http://dx.doi.org/10.1186/s12964-015-0089-7

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