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Tenascin‐C Aggravates Autoimmune Myocarditis via Dendritic Cell Activation and Th17 Cell Differentiation

BACKGROUND: Tenascin‐C (TN‐C), an extracellular matrix glycoprotein, appears at several important steps of cardiac development in the embryo, but is sparse in the normal adult heart. TN‐C re‐expresses under pathological conditions including myocarditis, and is closely associated with tissue injury a...

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Detalles Bibliográficos
Autores principales: Machino‐Ohtsuka, Tomoko, Tajiri, Kazuko, Kimura, Taizo, Sakai, Satoshi, Sato, Akira, Yoshida, Toshimichi, Hiroe, Michiaki, Yasutomi, Yasuhiro, Aonuma, Kazutaka, Imanaka‐Yoshida, Kyoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338691/
https://www.ncbi.nlm.nih.gov/pubmed/25376187
http://dx.doi.org/10.1161/JAHA.114.001052