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Regulated Inositol‐Requiring Protein 1‐Dependent Decay as a Mechanism of Corin RNA and Protein Deficiency in Advanced Human Systolic Heart Failure
BACKGROUND: The compensatory actions of the endogenous natriuretic peptide system require adequate processing of natriuretic peptide pro‐hormones into biologically active, carboxyl‐terminal fragments. Natriuretic peptide pro‐peptide processing is accomplished by corin, a transmembrane serine proteas...
Autores principales: | Lee, Rebecca, Xu, Bin, Rame, J. Eduardo, Felkin, Leanne E., Barton, Paul, Dries, Daniel L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338699/ https://www.ncbi.nlm.nih.gov/pubmed/25516437 http://dx.doi.org/10.1161/JAHA.114.001104 |
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