Regulated Inositol‐Requiring Protein 1‐Dependent Decay as a Mechanism of Corin RNA and Protein Deficiency in Advanced Human Systolic Heart Failure

BACKGROUND: The compensatory actions of the endogenous natriuretic peptide system require adequate processing of natriuretic peptide pro‐hormones into biologically active, carboxyl‐terminal fragments. Natriuretic peptide pro‐peptide processing is accomplished by corin, a transmembrane serine proteas...

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Detalles Bibliográficos
Autores principales: Lee, Rebecca, Xu, Bin, Rame, J. Eduardo, Felkin, Leanne E., Barton, Paul, Dries, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338699/
https://www.ncbi.nlm.nih.gov/pubmed/25516437
http://dx.doi.org/10.1161/JAHA.114.001104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338699/
https://www.ncbi.nlm.nih.gov/pubmed/25516437
http://dx.doi.org/10.1161/JAHA.114.001104

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