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Anti‐Inflammatory Immune Skewing Is Atheroprotective: Apoe(−/−)FcγRIIb(−/−) Mice Develop Fibrous Carotid Plaques

BACKGROUND: Stroke, caused by carotid plaque rupture, is a major cause of death in the United States. Whereas vulnerable human plaques have higher Fc receptor (FcγR) expression than their stable counterparts, how FcγR expression impacts plaque histology is unknown. We investigated the role of FcγRII...

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Detalles Bibliográficos
Autores principales: Harmon, Erin Y., Fronhofer, Van, Keller, Rebecca S., Feustel, Paul J., Zhu, Xinmei, Xu, Hao, Avram, Dorina, Jones, David M., Nagarajan, Shanmugam, Lennartz, Michelle R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338708/
https://www.ncbi.nlm.nih.gov/pubmed/25516435
http://dx.doi.org/10.1161/JAHA.114.001232