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Deficiency of Ataxia Telangiectasia Mutated Kinase Delays Inflammatory Response in the Heart Following Myocardial Infarction

BACKGROUND: Ataxia‐telangiectasia results from mutations in ataxia telangiectasia mutated kinase (ATM) gene. We recently reported that ATM deficiency attenuates left ventricular (LV) dysfunction and dilatation 7 days after myocardial infarction (MI) with increased apoptosis and fibrosis. Here we inv...

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Detalles Bibliográficos
Autores principales: Daniel, Laura L., Daniels, Christopher R., Harirforoosh, Saghar, Foster, Cerrone R., Singh, Mahipal, Singh, Krishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338722/
https://www.ncbi.nlm.nih.gov/pubmed/25520329
http://dx.doi.org/10.1161/JAHA.114.001286