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Iron alters cell survival in a mitochondria-dependent pathway in ovarian cancer cells

The role of iron in the development of cancer remains unclear. We previously reported that iron reduces cell survival in a Ras/mitogen-activated protein kinase (MAPK)-dependent manner in ovarian cells; however, the underlying downstream pathway leading to reduced survival was unclear. Although level...

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Detalles Bibliográficos
Autores principales: Bauckman, Kyle, Haller, Edward, Taran, Nicholas, Rockfield, Stephanie, Ruiz-Rivera, Abigail, Nanjundan, Meera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338747/
https://www.ncbi.nlm.nih.gov/pubmed/25697096
http://dx.doi.org/10.1042/BJ20140878