Cargando…

Tau Reduction Prevents Disease in a Mouse Model of Dravet Syndrome

OBJECTIVE: Reducing levels of the microtubule-associated protein tau has shown promise as a potential treatment strategy for diseases with secondary epileptic features such as Alzheimer disease. We wanted to determine whether tau reduction may also be of benefit in intractable genetic epilepsies. ME...

Descripción completa

Detalles Bibliográficos
Autores principales: Gheyara, Ania L, Ponnusamy, Ravikumar, Djukic, Biljana, Craft, Ryan J, Ho, Kaitlyn, Guo, Weikun, Finucane, Mariel M, Sanchez, Pascal E, Mucke, Lennart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338764/
https://www.ncbi.nlm.nih.gov/pubmed/25042160
http://dx.doi.org/10.1002/ana.24230