Design, synthesis, and computational studies on dihydropyrimidine scaffolds as potential lipoxygenase inhibitors and cancer chemopreventive agents

Dihydropyrimidine scaffold has a wide range of potential pharmacological activities such as antiviral, antitubercular, antimalarial, anti-inflammatory, and anticancer properties. 5-Lipoxygenase enzyme is an enzyme responsible for the metabolism of arachidonic acid to leukotrienes. The elevated level...

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Detalles Bibliográficos
Autores principales: Venugopala, Katharigatta N, Govender, Reshme, Khedr, Mohammed A, Venugopala, Rashmi, Aldhubiab, Bandar E, Harsha, Sree, Odhav, Bharti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338777/
https://www.ncbi.nlm.nih.gov/pubmed/25733811
http://dx.doi.org/10.2147/DDDT.S73890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338777/
https://www.ncbi.nlm.nih.gov/pubmed/25733811
http://dx.doi.org/10.2147/DDDT.S73890

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