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Computational analysis of the LRRK2 interactome

LRRK2 was identified in 2004 as the causative protein product of the Parkinson’s disease locus designated PARK8. In the decade since then, genetic studies have revealed at least 6 dominant mutations in LRRK2 linked to Parkinson’s disease, alongside one associated with cancer. It is now well establis...

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Detalles Bibliográficos
Autores principales: Manzoni, Claudia, Denny, Paul, Lovering, Ruth C., Lewis, Patrick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338795/
https://www.ncbi.nlm.nih.gov/pubmed/25737818
http://dx.doi.org/10.7717/peerj.778