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HDAC4 as a potential therapeutic target in neurodegenerative diseases: a summary of recent achievements
For the past decade protein acetylation has been shown to be a crucial post-transcriptional modification involved in the regulation of protein functions. Histone acetyltransferases (HATs) mediate acetylation of histones which results in the nucleosomal relaxation associated with gene expression. The...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338808/ https://www.ncbi.nlm.nih.gov/pubmed/25759639 http://dx.doi.org/10.3389/fncel.2015.00042 |