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HDAC4 as a potential therapeutic target in neurodegenerative diseases: a summary of recent achievements

For the past decade protein acetylation has been shown to be a crucial post-transcriptional modification involved in the regulation of protein functions. Histone acetyltransferases (HATs) mediate acetylation of histones which results in the nucleosomal relaxation associated with gene expression. The...

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Detalles Bibliográficos
Autores principales: Mielcarek, Michal, Zielonka, Daniel, Carnemolla, Alisia, Marcinkowski, Jerzy T., Guidez, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338808/
https://www.ncbi.nlm.nih.gov/pubmed/25759639
http://dx.doi.org/10.3389/fncel.2015.00042