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Mechanism of coupling drug transport reactions located in two different membranes

Gram- negative bacteria utilize a diverse array of multidrug transporters to pump toxic compounds out of the cell. Some transporters, together with periplasmic membrane fusion proteins (MFPs) and outer membrane channels, assemble trans-envelope complexes that expel multiple antibiotics across outer...

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Detalles Bibliográficos
Autores principales: Zgurskaya, Helen I., Weeks, Jon W., Ntreh, Abigail T., Nickels, Logan M., Wolloscheck, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338810/
https://www.ncbi.nlm.nih.gov/pubmed/25759685
http://dx.doi.org/10.3389/fmicb.2015.00100