A Novel Mathematical Model Describing Adaptive Cellular Drug Metabolism and Toxicity in the Chemoimmune System

Cells cope with the threat of xenobiotic stress by activating a complex molecular network that recognizes and eliminates chemically diverse toxic compounds. This “chemoimmune system” consists of cellular Phase I and Phase II metabolic enzymes, Phase 0 and Phase III ATP Binding Cassette (ABC) membran...

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Detalles Bibliográficos
Autores principales: Tóth, Attila, Brózik, Anna, Szakács, Gergely, Sarkadi, Balázs, Hegedüs, Tamás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338831/
https://www.ncbi.nlm.nih.gov/pubmed/25699998
http://dx.doi.org/10.1371/journal.pone.0115533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338831/
https://www.ncbi.nlm.nih.gov/pubmed/25699998
http://dx.doi.org/10.1371/journal.pone.0115533

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