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CSF beta-amyloid 1–42 – what are we measuring in Alzheimer's disease?

OBJECTIVE: To characterize biological and technical factors which influence cerebrospinal fluid (CSF) Alzheimer's disease (AD) biomarker levels, including the presence of apolipoprotein E (APOE) ε4 allele, AD diagnosis, Aβ-binding proteins, sample processing, and preanalytical handling. METHODS...

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Detalles Bibliográficos
Autores principales: Hu, William T, Watts, Kelly D, Shaw, Leslie M, Howell, Jennifer C, Trojanowski, John Q, Basra, Sundeep, Glass, Jonathan D, Lah, James J, Levey, Allan I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338954/
https://www.ncbi.nlm.nih.gov/pubmed/25750918
http://dx.doi.org/10.1002/acn3.160