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Developmental enhancers revealed by extensive DNA methylome maps of zebrafish early embryos

DNA methylation undergoes dynamic changes during development and cell differentiation. Recent genome-wide studies discovered that tissue-specific differentially methylated regions (DMRs) often overlap tissue-specific distal cis-regulatory elements. However, developmental DNA methylation dynamics of...

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Detalles Bibliográficos
Autores principales: Lee, Hyung Joo, Lowdon, Rebecca F, Maricque, Brett, Zhang, Bo, Stevens, Michael, Li, Daofeng, Johnson, Stephen L, Wang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339225/
https://www.ncbi.nlm.nih.gov/pubmed/25697895
http://dx.doi.org/10.1038/ncomms7315