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A comprehensive evaluation of ensembl, RefSeq, and UCSC annotations in the context of RNA-seq read mapping and gene quantification

BACKGROUND: RNA-Seq has become increasingly popular in transcriptome profiling. One aspect of transcriptome research is to quantify the expression levels of genomic elements, such as genes, their transcripts and exons. Acquiring a transcriptome expression profile requires genomic elements to be defi...

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Detalles Bibliográficos
Autores principales: Zhao, Shanrong, Zhang, Baohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339237/
https://www.ncbi.nlm.nih.gov/pubmed/25765860
http://dx.doi.org/10.1186/s12864-015-1308-8