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Orphan nuclear receptor NR4A2 induces transcription of the immunomodulatory peptide hormone prolactin

BACKGROUND: Nuclear receptor 4A2 (NR4A2) is an orphan nuclear receptor and constitutively active transcription factor expressed at elevated levels in inflamed joint tissues from patients with arthritis. Inflammatory mediators rapidly and potently induce NR4A2 expression in resident joint cells and i...

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Detalles Bibliográficos
Autores principales: McCoy, Joseph M, Walkenhorst, Dana E, McCauley, Keegan S, Elaasar, Hiba, Everett, Jordan R, Mix, Kimberlee S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339243/
https://www.ncbi.nlm.nih.gov/pubmed/25717285
http://dx.doi.org/10.1186/s12950-015-0059-2