Atropselective Syntheses of (−) and (+) Rugulotrosin A Utilizing Point-to-Axial Chirality Transfer

Chiral, dimeric natural products containing complex structures and interesting biological properties have inspired chemists and biologists for decades. A seven step total synthesis of the axially chiral, dimeric tetrahydroxanthone natural product rugulotrosin A is described. The synthesis employs a...

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Detalles Bibliográficos
Autores principales: Qin, Tian, Skraba-Joiner, Sarah L., Khalil, Zeinab G., Johnson, Richard P., Capon, Robert J., Porco, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339264/
https://www.ncbi.nlm.nih.gov/pubmed/25698333
http://dx.doi.org/10.1038/nchem.2173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339264/
https://www.ncbi.nlm.nih.gov/pubmed/25698333
http://dx.doi.org/10.1038/nchem.2173

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