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Atropselective Syntheses of (−) and (+) Rugulotrosin A Utilizing Point-to-Axial Chirality Transfer
Chiral, dimeric natural products containing complex structures and interesting biological properties have inspired chemists and biologists for decades. A seven step total synthesis of the axially chiral, dimeric tetrahydroxanthone natural product rugulotrosin A is described. The synthesis employs a...
Autores principales: | Qin, Tian, Skraba-Joiner, Sarah L., Khalil, Zeinab G., Johnson, Richard P., Capon, Robert J., Porco, John A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339264/ https://www.ncbi.nlm.nih.gov/pubmed/25698333 http://dx.doi.org/10.1038/nchem.2173 |
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