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Evaluation and improvements of clustering algorithms for detecting remote homologous protein families
BACKGROUND: An important problem in computational biology is the automatic detection of protein families (groups of homologous sequences). Clustering sequences into families is at the heart of most comparative studies dealing with protein evolution, structure, and function. Many methods have been de...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339679/ https://www.ncbi.nlm.nih.gov/pubmed/25651949 http://dx.doi.org/10.1186/s12859-014-0445-4 |